In force Publication date 01 Apr 15
Synthesis of main metabolites of several aromatase inhibitors and antiestrogens as reference compounds for doping analytics
Project description
Project Title: Synthesis of main metabolites of several aromatase inhibitors and antiestrogens as reference compounds for doping analytics
Researchers: J. Yli-Kauhaluoma, M. Vahermo (University of Helsinki, Finland), A. Leinonen (United Laboratories Ltd, Finland)
Year accepted: 2007
Summary: We propose to develop a high-yielding and selective synthesis method for the preparation of these metabolites or synthesize some of the metabolites according to the published methods. Although tamoxifen metabolite is commercially available, it will be synthesized for comparison purposes.