In force Publication date 18 Jan 17

In vivo metabolism studies on growth hormone releasing hormones and their detection by liquid chromatography-mass spectrometry

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Project Title: In vivo metabolism studies on growth hormone releasing hormones and their detection by liquid chromatography-mass spectrometry

Researchers: Pr. M. Thevis, Pr. W. Schänzer, Dr. A. Thomas

Institution: German Sport University, Germany

Year accepted: 2014

Summary: The main parts of the planned project are thus the characterization of metabolites of all GHRH analogues in a rat model (in-vivo) and human blood specimens (in-vitro). Subsequently, effective target peptides (intact drug or derived metabolites) will be evaluated in different biological fluids allowing to establish an initial test method as well as confirmatory procedure inclusive of all relevant target analytes.

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