In force Publication date 15 Nov 18
Unequivocal detection of AAV-mediated gene doping by pan-AAV immunological profiling
Project description
Project Title: Unequivocal detection of AAV-mediated gene doping by pan-AAV immunological profiling
Researchers: Drs. G. Ronzitti (INSERM U951, France), F. Bosch (Universitat Autònoma, Barcelona, Spain)
Year accepted: 2017
Summary: We propose the development of a method for unequivocal detection of AAV-mediated gene doping based on the hypothesis that gene transfer with AAV vectors will leave a characteristic immunological footprint clearly distinguishable from natural occurring AAV infections with wild-type virus.