In force Publication date 03 Mar 16
Ultra-Sensitive Mass Spectrometric Detection of a rEPO Specific O-glycopeptide as an Unambiguous Proof of Doping Follow-up (GOpep2)
Project Title: Ultra-Sensitive Mass Spectrometric Detection of a rEPO Specific O-lycopeptide as an Unambiguous Proof of Doping—Follow-up (GOpep2)
Researchers: Dr. J. Pascual, Dr. J. Segura
Institution: Fundacio IMIM (FIMIM), Spain
Year accepted: 2015
- To improve sample clean-up by using the already developed polyclonal antibody against the peptide backbone and other desalting techniques.
- To improve the nanoLC-MS/MS set-up using monolithic columns for high throughput and on-line sample clean-up.
- To develop monoclonal antibody for future use of the methodology if the use of the polyclonal proves successful.
- To validate the procedure in urine and serum sample
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