In force Publication date 01 Apr 15
Synthesis and in vitro metabolism studies of selective androgen receptor modulators (SARMs) currently undergoing clinical trial (llb)
Project Title: Synthesis and in vitro metabolism studies of selective androgen receptor modulators (SARMs) currently undergoing clinical trials (llb)
Researchers: M. Thevis, W. Schänzer (German Sports University, Cologne, Germany), R. Kostiainen, (University of Helsinki, Finland), T. Kuuranne, (United Laboratories Ltd, Finland)
Year accepted: 2007
Summary: In the course of the WADA-funded project concerning the metabolism of arylpropionamide-derived SARMs, a method to detect the unchanged drug candidates S-1, S-4, S-9, S-22, S-23, S-24, and a metabolite M-11 in human urine was established and validated using liquid chromatography/tandem mass spectrometry.
Available in 1 language.