In force Publication date 07 May 15

Synthesis and in-vitro metabolism of sirtuins: A class of emerging drugs with misuse potential in elite sport

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Project Title: Synthesis and in-vitro metabolism of sirtuins: A class of emerging drugs with misuse potential in elite sport

Researchers: Dr. Thevis, Dr. Schanzer 

Institution: German Sport University Cologne, Germany

Year accepted: 2011

Summary: Detection methods for blood and urine concerning the intact drugs and respective metabolic products will be developed, requiring the synthesis of model sirtuin activators, their in vitro metabolism (enabling the characterization of urinary metabolites), and finally the implementation of new target analytes in routine doping controls

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