Studies related to the metabolism of endogenously produced nandrolone and exogenously administered nandrolone precursors

Project Title: Studies related to the metabolism of endogenously produced nandrolone and exogenously administered nandrolone precursors

Researchers: P. Hemmersbach (Hormone Laboratory, University Hospital, Oslo, Norway), J. Grosse (Institute of Doping Analysis, Kreicha, Germany)

Year accepted: 2002

Summary: The project intends to study:

a) the nandrolone excretion of human granulosa cells,

b) the aromatisation of different amounts of testosterone in this aromatase rich medium with respect to nandrolone or norandrostenedione synthesis,

c) aromatase independent production of nandrolone,

d) the influence of aromatase inhibitors on these reactions, e) nandrolone as possible substrate for in vitro aromatisation