In force Publication date 01 Apr 15
Metabolism of steroids via humanized livers in mice
Project Title: Metabolism of steroids via humanized livers in mice
Researchers: F.T. Delbeke, G. Lerouxm Roels, P. Van Eenoo
Institution: Doping Control Laboratory, Ghent, Belgium
Year accepted: 2006
Summary: This study will evaluate an animal model in which mice harbouring a functional human liver will be used for investigation of the metabolism of steroids. In contrast to, in-vitro models using single cells or cell cultures, this animal uses a functional human liver and resembles administration studies better than any other model available so far.
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