In force Publication date 13 Apr 15

Implementation of HPLC/orbitrap mass spectrometry as a general screening method for doping control

Resource description

Project Title: Implementation of HPLC/orbitrap mass spectrometry as a general screening method for doping control

Researchers: G. Rodchenkov, E. Virus, M. Dikunets, E. Semenistay, T. Raduschina, T. Sobolevsky

Institution: Moscow Antidoping Centre, Department of Doping Control, Moscow, Russia

Year accepted: 2009

Summary: A full description and validation as a general screening method based on SPE and HPLC/orbitrap mass spectrometry with different ionization techniques for doping agents, including anabolic steroids, beta2-adrenergic agonists, SARMs, agents with antiestrogenic activity, diuretics, stimulants, beta-blockers, and cannabinoids. Validation of the method will consist of investigation of specificity, analytical recovery, limit of detection, and repeatability. Finally, a comparison of the HPLC/orbitrap mass spectrometry and HPLC/MS/MS methods for the qualitative screening of prohibited substances in urine will be performed.

Download options

Available in 1 language.