In force Publication date 01 Apr 15
Identification and characterization of transcriptional markers diagnostic of autologous blood doping
Project Title: Identification and characterization of transcriptional markers diagnostic of autologous blood doping
Researcher: J. Rupert
Institution: University of British Columbia, Vancouver, British Columbia, Canada
Year accepted: 2007
Summary: The project has three phases:
1) identification of transcripts in whole and leukodepleted blood that represent genes that are activated or up-regulated in blood cells in response to post-withdrawal processing and/or short-term storage;
2) use of simulated autologous blood doping to determine if these transcripts could be detected in a “doped” athlete; and
3) characterization of the inter- and intra-individual variation of the transcripts shown to have potential test utility under a variety of conditions experienced by athletes (e.g. physical exertion, hypoxia/altitude, time of day, and time in menstrual cycle).
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