Development of Ultrasensitive DNA Aptamer-Based Assays for Natural and Recombinant Human Growth Hormone in Serum and Urine

Project Title: Development of DNA Aptamers Against Growth Hormone-Releasing Peptides for Detection in Serum and Mass Spectral Analyses

Researcher: Dr. J. Bruno

Institution: Operational Technologies Corporation, USA

Year accepted: 2009

Summary: Under this project, Operational Technologies Corporation will develop high affinity and highly specific DNA aptamers to bind the GH-releasing peptides GHRP-6, Ipamorelin and the GHRP-2 main metabolite AA-3 (D-Ala-D-(beta-naphthyl)-Ala-Ala-O.