In force Publication date 20 Feb 15
Development of a prototype blood-based test for exogenous erythropoietin activity based on transcriptional profiling
Project Title: Development of a prototype blood-based test for endogenous erythropoietin activity based on transcriptional profiling
Researchers: J. Rupert, D. McKenzie
Institution: University of British Columbia, Vancouver, Canada
Year accepted: 2005
Summary: In our project, Serial Analysis Gene Expression is being used to compare the transcriptional profile of the hypoxia response to that of foreign EPO activity. We hypothesize that comparing these profiles will identify differentially expressed genes that can be used to develop a diagnostic test. We will identify these genes in a mouse model, locate and characterize their human counterparts, and incorporate the latter into blood-based test for exogenous EPO expression.
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