In force Publication date 12 May 15
Exploring the potentials of transcriptomic and novel micro RNA screening approaches for the indirect detection of gene doping
Resource description
Project Title: Exploring the potentials of transcriptomic and novel micro RNA screening approaches for the indirect detection of gene doping
Researchers: P. Simon, M. Giacca, S. Tug
Institution: Johannes Gutenberg-University Mainz, Germany
Year accepted: 2010
Summary: In this project we will exploit the possibility to detect molecular signatures of gene doping based on the level of proteins (proteome), RNAs (transcriptome) or the non-coding, regulatory microRNA that are modified upon modifications of the pathways induced by IGF1 and HIF1a, the former improving muscle properties and the latter increasing oxygen delivery and aerobic capacity.