In force Publication date 12 May 15

Exploring the potentials of transcriptomic and novel micro RNA screening approaches for the indirect detection of gene doping

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Project Title: Exploring the potentials of transcriptomic and novel micro RNA screening approaches for the indirect detection of gene doping

Researchers: P. Simon, M. Giacca, S. Tug

Institution: Johannes Gutenberg-University Mainz, Germany

Year accepted: 2010

Summary: In this project we will exploit the possibility to detect molecular signatures of gene doping based on the level of proteins (proteome), RNAs (transcriptome) or the non-coding, regulatory microRNA that are modified upon modifications of the pathways induced by IGF1 and HIF1a, the former improving muscle properties and the latter increasing oxygen delivery and aerobic capacity.

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