In force Publication date 21 Mar 16
a) A systems biology biomarker based approach to the detection of microdose recombinant human erythropoietin doping and b) Metabolomic profiling of recombinant erythropoietin in caucasian and east-African endurance trained athletes
Resource description
Project Titles:
- a) A systems biology biomarker based approach to the detection of microdose recombinant human erythropoietin doping
- b) Metabolomic profiling of recombinant erythropoietin in caucasian and east-African endurance trained athletes
Researchers: Dr. Y. Pitsiladis, Dr G. Gmeiner, Dr. M. Ashenden, Dr. D. Watson, Ms. E. Daskalaki, Jérôme Durussel
Institution(s): University of Glasgow, UK; Seibersdorf Laboratory, Austria, SIAB, Australia
Year accepted: 2012
Summary:
- a) The purpose of a research project funded by WADA in 2008 entitled “A gene-microarray based approach to the detection of recombination human erythropoietin doping in endurance athletes” was to develop new methods with improved discriminatory power relative to current detection protocols based on gene expression profiles.
- b) We propose the addition of metabolomics (high resolution mass spectrometry methods) to the established research study aimed at identifying new metabolomic biomarkers that can differentiate between r-HuEpo administration and chronic altitude exposure (using samples already collected from WADA-funded studies).