In force Publication date 10 Feb 15
Mass spectrometric characterization and identification of endogenous and synthetic insulins
Resource description
Project Title: Mass spectrometric characterization and identification of endogenous and synthetic insulins
Researchers: W. Schänzer, M. Thevis
Institution: German Sport University, Cologne, Germany
Year accepted: 2003
Summary: In order to identify rapid- and long-acting insulins, their mass spectrometric properties after electrospray ionization have to be elucidated. As differences of endogenous and synthetic insulins are limited to exchanges of few amino acids, and one compound is identical with human insulin regarding molecular weight, product ion experiments have to be optimized to efficiently analyze the target compounds in low concentrations in biological fluids.