Investigation of the applicability of dried blood spots for the analysis of glucocorticoids

Code: 242C03WCWC

Glucocorticoids (GCs) are widely used in medicine among athletes and are prohibited in competition only when administered orally, rectally, or by injection. However, an in-competition urine sample may show GC levels above the established laboratory reporting levels even if the administration occurred out-of-competition. Urinary washout periods have been established to mitigate this risk. Since blood levels correlate better with substance exposure than urine, dried blood spots (DBSs) collected through microsampling may provide valuable support in determining the timing of GC administration.