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June 15, 2011 to June 16, 2011
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Developments and Challenges in the Detection of Doping with Peptide Hormones Symposium - Rome 2011

Rome, Italy

On June 15-16, 2011, WADA, in collaboration with the Italian Federation of Sports Medicine (FMSI), held a Symposium on developments and challenges in the detection of doping with peptide hormones, in Rome.

Although considerable progress has been made over the past few years, the detection of peptide hormones remains one of the most challenging aspects in the fight against doping in sport.

During this two-day meeting, participants reviewed recent advances and discussed cutting-edge techniques that could improve the detection of peptide hormones and related substances, including:

  • New selective chromatographic and mass spectrometric methods for protein detection.
  • Strategies for protein quantification.
  • Glycan analysis of proteins. 
  • Surface plasmon resonance, affinity-based biosensors and aptamers for antidoping applications.
  • Proteomic / metabolonomic approaches to identify biomarkers of doping.

The conclusions will be used to strengthen the development of some of the strategies under consideration for the detection of doping with peptide hormones and biosimilars.

Click here for the concluding remarks.


Presentations

Wednesday, 15 June 2011

  1. uHPLC/MS/MS-Based SRM for Biomarkers of rhGH Administration (P. Teale)
  2. Application of MS to Quantification of hGH (D. Desiderio)
  3. Structural Elucidation of Glycans as a Tool to Differentiate Recombinant from Endogenous Glycoproteins (T. Pascual)
  4. Analysis of Growth Hormone Releasing Peptide GHRP-2 for Doping Control Purposes (Dr. Kageyama) 

Thursday, 16 June 2011

  1. Nanoparticles-Based Extraction-Capillary Zone Electrophoresis-Native Fluorescence Detection of EPO (Z. Liu)
  2. Multiplexing of Protein Detection Capabilities (M. Ueki)
  3. Application of Nanotechnology and SPR to Doping Control (F. Mazzei)
  4. Use of DNA Aptamers as Analytical Tools for Anti-Doping Peptide (rhGH) Analysis (J. Bruno)
  5. Affinity-Based Biosensors (ABB) for Anti-Doping Applications (Dr. Minunni)